Posted on: July 5, 2022
New BCCDC Therapeutic Document: Both ritonavir and nirmatrelvir (components of Paxlovid) can be split or crushed and mixed with apple sauce, pudding or any common food or liquid including dairy-containing products based on Phase I studies demonstrating that suspensions achieve similar pharmacokinetics to whole tablets. Both ritonavir and nirmatrelvir be crushed and mixed with water to the desired consistency and considered for administration via feeding tubes; the tube should be flushed with water after administration. These recommendations do not replace clinical judgement